A new study by Brain Sciences shows that prolonged use of medical cannabis could help reduce the frequency of long-term migraines for the majority of people affected and decrease medication intake.
The researchers point out that while most pharmaceutical research is based on a single chemical compound approach, cannabis treatment with the whole plant is linked to several molecules, according to the American Journal of Managed Care.
In addition to THC and CBD, the cannabis plant contains many more active compounds. The researchers sought to “study the total doses of individual phytocannnabinoids consumed by migraine sufferers and to explore the differences in dosage between subgroups of patients based on changes in the frequency of migraine.”
Only phytocannnabinoids consumed with a minimum average concentration of 0.1 grams per month were analyzed, and doses were calculated for each patient.
The researchers were encouraged by the recent findings of the cross-sectional questionnaire study, a feeling that is likely shared by the 1 to 2% of the world’s population who suffer from chronic migraines.
What about the results? 61% of those who responded to the questionnaire and received migraine treatment for an average of three years reported having much less common migraines, and lower intakes of opioids and triptans (drugs commonly used for treatment), the study notes.
Participants also reported better sleep quality, although investigators were unable to confirm whether this was related to a decrease in migraine attacks or whether this was the result of medical treatment with cannabis.
The researchers add that “endocannabinoids have an inhibitory effect on serotonin receptors in vivo, which modulate pain and emetic responses.”
“While the available evidence suggests involvement of the endocannabinoid system and potential for therapeutic treatment of migraine with medical cannabis, further research is needed to demonstrate the effectiveness of the treatment of migraine with medical cannabis,” they add.
Kanabiz will keep you informed of the evolution of this research, which will undoubtedly benefit all people suffering from migraines!